2-Morpholinoethylamine → HCID 46932608, compound

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Reaction Steps

Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (100 mg, 0.28 mmol) and 4-(2-aminoethyl) morpholine (42 mg, 0.32 mmol). The title compound was obtained as a solid (49 mg, 38% yield). 1H NMR (400 MHz, d6-DMSO) δ: 8.98 (2H, m), 8.83 (1H, m), 8.43 (1H, s), 4.02 (4H, m), 3.31 (2H, m), 2.45 (2H, m), 2.38 (4H, m). MS m/z: 463.06, 465.05 [M+H]+.

Provenance & Evidence