HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine tert-butyl ester → HCID 67494833, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine tert-butyl ester | HCID 151417 | — |
| Reactant | 5-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid | HCID 60207317 | — |
| Product | HCID 67494833 | HCID 67494833 | — |
Reaction Steps
Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (145 mg, 0.5 mmol) and tert-butyl 2-aminoacetate (79 mg, 0.6 mmol). The title compound was obtained as a solid (98.0 mg, 42% yield). 1H NMR (300 MHz, d6-DMSO) δ: 8.74 (2H, s), 7.95 (1H, s), 4.06 (2H, m), 1.49 (9H, s) MS m/z: 463.80, 465.75 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680139B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-1d3f385c07414f66bb4041134922f286 |
| Source note | uspto-grants-2014_03 |