2-Amino-4,5-dimethyl-1,3-thiazole → HCID 60207329, compound

Participants

Reaction Steps

Prepared according to the procedure described for example 70 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (200 mg, 0.57 mmol) and 4,5-dimethyl-thiazol-2-amine (87 mg, 0.68 mmol). The title compound was obtained as a yellow solid (8 mg, 3% yield). 1H NMR (400 MHz, d6-DMSO) δ: 12.85 (1H, m), 9.01 (2H, m), 2.08 (6H, m). MS m/z: 459.03, 461.02 [M+H]+.

Provenance & Evidence