(3-(Methylsulfonyl)phenyl)methanamine → HCID 60207361, compound

HRID 1192142Notes

Reaction equation

HRID 1192142 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][S:22]([C:25]1[CH:26]=[C:27]([CH2:31][NH2:32])[CH:28]=[CH:29][CH:30]=1)(=[O:24])=[O:23]>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:32][CH2:31][C:27]2[CH:28]=[CH:29][CH:30]=[C:25]([S:22]([CH3:21])(=[O:24])=[O:23])[CH:26]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 2760937(3-(Methylsulfonyl)phenyl)methanamineHCID 602073175-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid

Product 1

HCID 60207361HCID 60207361, compound

Procedure

Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and (3-methylsulfonylphenyl)methanamine (22.0 mg, 0.12 mmol). The title compound was obtained as a solid (22.8 mg, 44% yield). MS m/z: 517.95, 519.95 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a6bdef2d9bfd4e01bc401c7d6105c557
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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