N-Methyl-1-[3-(methylsulfanyl)phenyl]methanamine → HCID 60207363, compound

HRID 1192144Notes

Reaction equation

HRID 1192144 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][NH:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([S:30][CH3:31])[CH:25]=1>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([N:22]([CH3:21])[CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([S:30][CH3:31])[CH:25]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 26722448N-Methyl-1-[3-(methylsulfanyl)phenyl]methanamineHCID 602073175-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid

Product 1

HCID 60207363HCID 60207363, compound

Procedure

Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and N-methyl-1-(3-methylsulfanylphenyl)methanamine (17.0 mg, 0.12 mmol). The title compound was obtained as a solid (33.5 mg, 67% yield). MS m/z: 500.01, 502.00 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f097c5da4dff46068e544f572688233b
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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