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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1192146Generated: October 30, 2026

4-(Methylsulfonyl)aniline → HCID 60207365, compound

https://huagongshe.com/reaction/1192146

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylsulfonyl)anilineHCID 79617—
Reactant5-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carbonyl chlorideHCID 60207337—
ProductHCID 60207365HCID 60207365—

Reaction Steps

Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carbonyl chloride (120 mg, 0.33 mmol) and 4-methylsulfonylaniline (66 mg, 0.39 mmol). The title compound was obtained as a yellow solid (60 mg, 37% yield). 1H NMR (400 MHz, d6-DMSO) δ: 10.88 (1H, m), 9.01 (2H, s), 8.87 (1H, s), 7.96 (4H, s), 3.20 (3H, s). MS m/z: 502.04, 503.99 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08680139B2
Source datasetuspto-grants-2014_03
ORD IDord-d5ad30e81139425dafc06841ab825c87
Source noteuspto-grants-2014_03