2-Chloroaniline → HCID 60207370, compound

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Reaction Steps

Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carbonyl chloride (120 mg, 0.33 mmol) and 2-chloro-aniline (49 mg, 0.39 mmol). The title compound was obtained as a solid (42 mg, 28% yield). 1H NMR (400 MHz, d6-DMSO) δ: 10.53 (1H, s), 8.99 (2H, s), 8.61 (1H, s), 7.55 (1H, m), 7.47 (1H, m), 7.38 (2H, m), 7.32 (1H, m). MS m/z: 458.07, 460.05 [M+H]+.

Provenance & Evidence