HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-(trifluoromethyl)aniline → HCID 60207373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-(trifluoromethyl)aniline | HCID 67853 | — |
| Reactant | 5-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carbonyl chloride | HCID 60207337 | — |
| Product | HCID 60207373 | HCID 60207373 | — |
Reaction Steps
Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carbonyl chloride (120 mg, 0.33 mmol) and 4-fluoro-2-trifluoromethyl-aniline (69 mg, 0.39 mmol). The title compound was obtained as a solid (60 mg, 36% yield). 1H NMR (400 MHz, d6-DMSO) δ: 10.55 (1H, s), 8.99 (2H, m), 8.64 (1H, s), 7.73 (1H, m), 7.64 (1H, m), 7.58 (1H, m). MS m/z: 510.02, 512.00 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680139B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-6fc3a9cda56741c783adaaf7788e197a |
| Source note | uspto-grants-2014_03 |