3-Methoxyaniline → HCID 60207385, compound

HRID 1192169Notes

Reaction equation

HRID 1192169 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14](Cl)=[O:15])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][O:22][C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([NH2:29])[CH:24]=1>>[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:29][C:25]2[CH:26]=[CH:27][CH:28]=[C:23]([O:22][CH3:21])[CH:24]=2)=[O:15])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 108243-MethoxyanilineHCID 602073375-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carbonyl chloride

Product 1

HCID 60207385HCID 60207385, compound

Procedure

Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carbonyl chloride (120 mg, 0.33 mmol) and m-anisidine (60 mg, 0.39 mmol). The title compound was obtained as a solid (27 mg, 15% yield). 1H NMR (400 MHz, d6-DMSO) δ: 10.49 (1H, s), 9.01 (2H, s), 8.73 (1H, m), 7.31 (1H, m), 7.26 (2H, m), 6.70 (1H, m), 3.80 (3H, s). MS m/z: 454.09, 456.04 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8dc49cd9ed514bb8922fee34d86e8a25
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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