2-Methyl-2H-pyrazol-3-ylamine → HCID 60207395, compound

HRID 1192179Notes

Reaction equation

HRID 1192179 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][N:22]1[C:26]([NH2:27])=[CH:25][CH:24]=[N:23]1>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:27][C:26]2[N:22]([CH3:21])[N:23]=[CH:24][CH:25]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 1369272-Methyl-2H-pyrazol-3-ylamineHCID 602073175-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid

Product 1

HCID 60207395HCID 60207395, compound

Procedure

Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and 2-methylpyrazol-3-amine (9.7 mg, 0.12 mmol). The title compound was obtained as a solid (10.0 mg, 23% yield). MS m/z: 429.96, 431.96 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2ea2968459304948b2ad096426462a83
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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