3-Aminoquinoline → HCID 60207400, compound

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Prepared according to the procedure described for example 70 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (150 mg, 0.43 mmol) and 3-aminoquinoline (73.7 mg, 0.51 mmol). The title compound was obtained as a yellow solid (40 mg, 20% yield). 1H NMR (400 MHz, d6-DMSO) δ: 10.97 (1H, br), 9.066 (1H, m), 9.02 (2H, m), 8.77 (1H, m), 8.65 (1H, m), 7.95 (2H, m), 7.69 (1H, m), 7.59 (1H, m). MS m/z: 475.23, 477.28 [M+H]+.

Provenance & Evidence