1H-1,2,4-Triazol-3-amine, 1-ethyl- → HCID 60207410, compound

HRID 1192195Notes

Reaction equation

HRID 1192195 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH2:21]([N:23]1[CH:27]=[N:26][C:25]([NH2:28])=[N:24]1)[CH3:22]>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:28][C:25]2[N:26]=[CH:27][N:23]([CH2:21][CH3:22])[N:24]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 1426191H-1,2,4-Triazol-3-amine, 1-ethyl-HCID 602073175-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid

Product 1

HCID 60207410HCID 60207410, compound

Procedure

Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and 1-ethyl-1H-1,2,4-triazol-3-amine (11.2 mg, 0.12 mmol). The title compound was obtained as a solid (8.9 mg, 20% yield). MS m/z: 466.95, 468.95 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fc0cc3a8f8424f0382fd4b4c6a3ca4e8
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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