3-Methoxypropylamine → HCID 60207439, compound

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Reaction Steps

Prepared according to the procedure described for example 70 from 2-(5-((3,5-dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxamido)acetic acid (120.0 mg, 0.29 mmol) from example 210 and 3-methoxypropylamine (31.4 mg, 0.35 mmol). The title compound was obtained as a solid (20.0 mg, 15% yield). 1H NMR (400 MHz, d6-DMSO) δ: 9.19 (1H, m), 8.99 (2H, m), 8.47 (1H, s), 7.94 (1H, m), 3.77 (2H, m), 3.29 (2H, m), 3.19 (3H, s), 3.07 (2H, m), 1.60 (2H, m). MS m/z: 477.11, 479.10 [M+H]+.

Provenance & Evidence