1-(Propan-2-yl)piperidin-4-amine → HCID 60207482, compound

HRID 1192261Notes

Reaction equation

HRID 1192261 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][C:11]1[S:15][C:14]([C:16]([OH:18])=O)=[CH:13][C:12]=1[N+:19]([O-:21])=[O:20].[CH:22]([N:25]1[CH2:30][CH2:29][CH:28]([NH2:31])[CH2:27][CH2:26]1)([CH3:24])[CH3:23]>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][C:11]1[S:15][C:14]([C:16]([NH:31][CH:28]2[CH2:29][CH2:30][N:25]([CH:22]([CH3:24])[CH3:23])[CH2:26][CH2:27]2)=[O:18])=[CH:13][C:12]=1[N+:19]([O-:21])=[O:20]

Participants

3

Reactant 2

HCID 31633331-(Propan-2-yl)piperidin-4-amineHCID 60207480HCID 60207480, compound

Product 1

HCID 60207482HCID 60207482, compound

Procedure

Prepared according to the procedure described for example 44 from 5-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-thiophene-2-carboxylic acid as in step A of example 256 (34 mg, 0.1 mmol) and 1-isopropylpiperidin-4-amine (17.0 mg, 0.12 mmol). The title compound was obtained as a solid (6.5 mg, 15% yield). MS m/z: 463.09, 465.09 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-257d3d3cea8f44b0af5b469dfa1b2ab7
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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