4-(3-(Dimethylamino)propoxy)aniline → HCID 67495153, compound

HRID 1192265Notes

Reaction equation

HRID 1192265 reaction equation
[F:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([F:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][N:22]([CH3:34])[CH2:23][CH2:24][CH2:25][O:26][C:27]1[CH:33]=[CH:32][C:30]([NH2:31])=[CH:29][CH:28]=1>>[F:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([F:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:31][C:30]2[CH:29]=[CH:28][C:27]([O:26][CH2:25][CH2:24][CH2:23][N:22]([CH3:21])[CH3:34])=[CH:33][CH:32]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 100584694-(3-(Dimethylamino)propoxy)anilineHCID 60207486HCID 60207486, compound

Product 1

HCID 67495153HCID 67495153, compound

Procedure

Prepared according to the procedure described for example 44 from 5-((3,5-difluoropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid (25 mg, 0.79 mmol) and 4-(3-(dimethylamino)propoxy)aniline (26.7 mg, 0.79 mmol). The title compound was obtained as a solid (12 mg, 15%). MS m/z: 495.10, [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c8ee9d05202a4e5082dfb02c83e8878c
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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