Chloroform → 3-{[(2,4-Dichlorobenzyl)-(3-oxo-butyl)-amino]-methyl}-azetidine-1-carboxylic acid tert-butyl ester

HRID 119236Notes

Reaction equation

HRID 119236 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:12][NH:13][CH2:14][c:15]2[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:11]1.[CH:23](=[CH2:24])[C:25](=[O:26])[CH3:27].[Cl:28][CH:29]([Cl:30])[Cl:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:12][N:13]([CH2:14][c:15]2[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:24][CH2:23][C:25](=[O:26])[CH3:27])[CH2:11]1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 6570Methyl vinyl ketoneHCID 690029773-[(2,4-Dichlorobenzylamino)-methyl]-azetidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 690048573-{[(2,4-Dichlorobenzyl)-(3-oxo-butyl)-amino]-methyl}-azetidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-728da7b512b04f479b1b2ff80abeadfd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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