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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11928Generated: October 25, 2026

(R)-1-(2-tert-Butoxycarbonylamino-1-methyl-ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester → (R)-4-Methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one

https://huagongshe.com/reaction/11928

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-1-(2-tert-Butoxycarbonylamino-1-methyl-ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl esterHCID 69556545—
Reactant(4R,9aR)-6-bromo-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl esterHCID 86590113—
Product(R)-4-Methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-oneHCID 69556684—

Reaction Steps

This compound was prepared in analogy to Example 1 intermediate b), from (R)-1-(2-tert-butoxycarbonylamino-1-methyl-ethyl)-1H-pyrrolo [2,3-b]pyridine-2-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098337B2
Source datasetuspto-grants-2006_08
ORD IDord-ba91640e69894163ae5a9e5f20c566cd
Source noteuspto-grants-2006_08