2,5-Dichloropyrimidine → HCID 57632911, compound

HRID 1192812Notes

Reaction equation

HRID 1192812 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5](Cl)=[CH:4][N:3]=1.[CH:9]([C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1)=[O:10]>[Pd]>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:14]2[CH:15]=[CH:16][C:11]([CH:9]=[O:10])=[CH:12][CH:13]=2)=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 5906412,5-DichloropyrimidineHCID 5910734-Formylphenylboronic Acid

Product 1

HCID 57632911HCID 57632911, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The compound was prepared by palladium-catalyzed arylation of 2,5-dichloropyrimidine and 4-formylphenyl boronic acid.

Sources & evidence

ORD record
ord-3c575146fcfe4ecf8787934839076206
Source dataset
uspto-grants-2014_03
Patent number
US08680269B2

Reaction notes

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