HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloroethyl N-(4-octylphenyl)sulfamoylcarbamate → Ethyl 2-(1-methyl-4-(N-(4-octylphenyl)sulfamoylamino)piperidin-4-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloroethyl N-(4-octylphenyl)sulfamoylcarbamate | HCID 58109976 | — |
| Reactant | Ethyl 2-(4-amino-1-methylpiperidin-4-yl)acetate | HCID 66865496 | — |
| Product | Ethyl 2-(1-methyl-4-(N-(4-octylphenyl)sulfamoylamino)piperidin-4-yl)acetate | HCID 66865130 | 34.2% |
Reaction Steps
According to the method described in example 15a, ethyl 2-(4-amino-1-methylpiperidin-4-yl)acetate (70 mg, 0.35 mmol) and 2-chloroethyl N-(4-octylphenyl)sulfamoylcarbamate (195 mg, 0.5 mmol) were reacted to yield the title compound (56 mg, 34%). MS ESI 468.4 [M+H]+, calcd for [C24H41N3O4S+H]+ 468.29.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680282B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-18064c7f7c244e46aece9f85fb60e2a3 |
| Source note | uspto-grants-2014_03 |