HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentanal, 5,5-dimethoxy- → (E)-6-nitro-7-p-tolylhept-5-enal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentanal, 5,5-dimethoxy- | HCID 170903 | — |
| Reactant | 1-Methyl-4-(2-nitroethyl)benzene | HCID 11228988 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | (E)-6-nitro-7-p-tolylhept-5-enal | HCID 58434561 | 35% |
Reaction Steps
Prepared according to the general procedure B from 1-methyl-4-(2-nitroethyl)benzene 112f (24 mmol) and 5,5-dimethoxypentanal 131 (16 mmol) to provide the title compound as yellow oil (1.38 g, 35% yield) after silica gel chromatography (EtOAc/Hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680335B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-2d70649003f54a99891b9c95a32471c4 |
| Source note | uspto-grants-2014_03 |