HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-2-picoline → (1R,6S)-8-(4,6-Dimethylpyridin-2-yl)-3,8-diazabicyclo[4.2.0]octane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-2-picoline | HCID 87601 | — |
| Reactant | (1R,6S)-8-(6-Methylpyridin-2-yl)-3,8-diazabicyclo[4.2.0]octane | HCID 67116915 | — |
| Product | (1R,6S)-8-(4,6-Dimethylpyridin-2-yl)-3,8-diazabicyclo[4.2.0]octane | HCID 67117261 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Intermediate 40, substituting 2-chloro-4,6-dimethylpyridine for 2-chloro-6-methylpyridine in step A. MS (ESI) mass calcd. for C13H19N3, 217.2; m/z found, 218.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680275B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-fac5cce66ff6408b90caed5fe016aa78 |
| Source note | uspto-grants-2014_03 |