2-Chloro-4-phenylpyrimidine → HCID 52919053, compound

HRID 1193151Notes

Reaction equation

HRID 1193151 reaction equation
C12N(C3C=NC4C(=CC=CC=4)N=3)CC1CCNC2.[C:19]1([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([N:27]1[CH2:33][CH:32]2[CH:29]([CH2:30][NH:31]2)[CH2:28]1)=[O:26].Cl[C:41]1[N:46]=[C:45]([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)[CH:44]=[CH:43][N:42]=1>>[C:19]1([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([N:27]1[CH2:33][CH:32]2[CH:29]([CH2:30][N:31]2[C:41]2[N:46]=[C:45]([C:47]3[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=3)[CH:44]=[CH:43][N:42]=2)[CH2:28]1)=[O:26]

Participants

4

Reactant 3

HCID 6053562-Chloro-4-phenylpyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 67116907HCID 67116907, compound

Product 1

HCID 52919053HCID 52919053, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 19 and 2-chloro-4-phenyl-pyrimidine. MS (ESI) mass calcd. for C28H24N4O, 432.53; m/z found, 433.3 [M+H]+.

Sources & evidence

ORD record
ord-ebdcfeb4728b45c08b126491bdbd2843
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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