2-Chloro-4-phenylpyrimidine → HCID 52919178, compound

HRID 1193155Notes

Reaction equation

HRID 1193155 reaction equation
C12N(C3C=NC4C(=CC=CC=4)N=3)CC1CCNC2.[CH:19]12[CH2:25][NH:24][CH:23]1[CH2:22][N:21]([C:26]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=1[O:34][CH3:35])=[O:27])[CH2:20]2.Cl[C:37]1[N:42]=[C:41]([C:43]2[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=2)[CH:40]=[CH:39][N:38]=1>>[CH3:35][O:34][C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=1[C:26]([N:21]1[CH2:22][CH:23]2[CH:19]([CH2:25][N:24]2[C:37]2[N:42]=[C:41]([C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)[CH:40]=[CH:39][N:38]=2)[CH2:20]1)=[O:27]

Participants

4

Reactant 3

HCID 6053562-Chloro-4-phenylpyrimidineHCID 67116634HCID 67116634, compoundHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxaline

Product 1

HCID 52919178HCID 52919178, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 22 and 2-chloro-4-phenyl-pyrimidine. MS (ESI) mass calcd. for C23H22N4O, 386.46; m/z found, 387.0 [M+H]+.

Sources & evidence

ORD record
ord-c81a8d9c6ba044f99d0e4363e3972f7f
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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