2-Chloro-4-methylpyrimidine → HCID 67116633, compound

HRID 1193158Notes

Reaction equation

HRID 1193158 reaction equation
C12[N:8]([C:9]3C=N[C:16]4[C:11](=CC=[CH:14][CH:15]=4)[N:10]=3)CC1CCNC2.[Br:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]([N:28]1[CH2:34][CH:33]2[CH:30]([CH2:31][NH:32]2)[CH2:29]1)=[O:27].ClC1N=C(C)C=CN=1>>[Br:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]([N:28]1[CH2:34][CH:33]2[CH:30]([CH2:31][N:32]2[C:9]2[N:8]=[C:15]([CH3:14])[CH:16]=[CH:11][N:10]=2)[CH2:29]1)=[O:27]

Participants

4

Reactant 3

HCID 116296072-Chloro-4-methylpyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 69932326HCID 69932326, compound

Product 1

HCID 67116633HCID 67116633, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 23 and 2-chloro-4-methylpyrimidine. MS (ESI) mass calcd. for C17H17BrN4O, 373.26; m/z found, 373.1 [M+H]+.

Sources & evidence

ORD record
ord-2ed1906b79a84a8cb60d6cb127e7b424
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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