2-Chloro-4-methylpyrimidine → HCID 52919303, compound

HRID 1193159Notes

Reaction equation

HRID 1193159 reaction equation
C12[N:8]([C:9]3C=N[C:16]4[C:11](=CC=[CH:14][CH:15]=4)[N:10]=3)CC1CCNC2.[C:19]1([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([N:27]1[CH2:33][CH:32]2[CH:29]([CH2:30][NH:31]2)[CH2:28]1)=[O:26].ClC1N=C(C)C=CN=1>>[C:19]1([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([N:27]1[CH2:33][CH:32]2[CH:29]([CH2:30][N:31]2[C:9]2[N:8]=[C:15]([CH3:14])[CH:16]=[CH:11][N:10]=2)[CH2:28]1)=[O:26]

Participants

4

Reactant 3

HCID 116296072-Chloro-4-methylpyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 67116907HCID 67116907, compound

Product 1

HCID 52919303HCID 52919303, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 19 and 2-chloro-4-methylpyrimidine. MS (ESI) mass calcd. for C23H22N4O, 370.46; m/z found, 371.2 [M+H]+.

Sources & evidence

ORD record
ord-cf6308740db9486fa024ae0e59730ff9
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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