2-Chloro-4-methoxypyrimidine → HCID 52919305, compound

HRID 1193160Notes

Reaction equation

HRID 1193160 reaction equation
C12N(C3C=NC4C(=CC=CC=4)N=3)CC1CCNC2.[C:19]1([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([N:27]1[CH2:33][CH:32]2[CH:29]([CH2:30][NH:31]2)[CH2:28]1)=[O:26].Cl[C:41]1[N:46]=[C:45]([O:47][CH3:48])[CH:44]=[CH:43][N:42]=1>>[C:19]1([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]([N:27]1[CH2:33][CH:32]2[CH:29]([CH2:30][N:31]2[C:41]2[N:46]=[C:45]([O:47][CH3:48])[CH:44]=[CH:43][N:42]=2)[CH2:28]1)=[O:26]

Participants

4

Reactant 3

HCID 5889352-Chloro-4-methoxypyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 67116907HCID 67116907, compound

Product 1

HCID 52919305HCID 52919305, compound

Procedure

The title compound was prepared in a manner analogous to for Intermediate 2, Step A, using Intermediate 19 and 2-chloro-4-methoxypyrimidine. MS (ESI) mass calcd. for C23H22N4O2, 386.46; m/z found, 387.2 [M+H]+.

Sources & evidence

ORD record
ord-876122f37a5b47faa89ddc856d1ed137
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

Loading…