2-Chloro-4,6-dimethoxypyrimidine → HCID 52919306, compound

HRID 1193161Notes

Reaction equation

HRID 1193161 reaction equation
C12N(C3C=NC4C(=CC=CC=4)N=3)CC1CCNC2.[CH:19]12[CH2:25][NH:24][CH:23]1[CH2:22][N:21]([C:26]([C:28]1[C:37]3[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=3)[CH:31]=[CH:30][C:29]=1[O:38][CH2:39][CH3:40])=[O:27])[CH2:20]2.Cl[C:42]1[N:47]=[C:46]([O:48][CH3:49])[CH:45]=[C:44]([O:50][CH3:51])[N:43]=1>>[CH3:51][O:50][C:44]1[CH:45]=[C:46]([O:48][CH3:49])[N:47]=[C:42]([N:24]2[CH2:25][CH:19]3[CH:23]2[CH2:22][N:21]([C:26]([C:28]2[C:37]4[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=4)[CH:31]=[CH:30][C:29]=2[O:38][CH2:39][CH3:40])=[O:27])[CH2:20]3)[N:43]=1

Participants

4

Reactant 3

HCID 51523232-Chloro-4,6-dimethoxypyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 67116914HCID 67116914, compound

Product 1

HCID 52919306HCID 52919306, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 24 and 2-chloro-4,6-dimethoxypyrimidine. MS (ESI) mass calcd. for C24H26N4O4, 434.5; m/z found, 435.2 [M+H]+.

Sources & evidence

ORD record
ord-d23415e234fe400fa673b060b17ad72e
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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