2-Chloro-4,6-dimethylpyrimidine → HCID 52919307, compound

HRID 1193162Notes

Reaction equation

HRID 1193162 reaction equation
C12[N:8]([C:9]3C=N[C:16]4[C:11](=[CH:12]C=[CH:14][CH:15]=4)[N:10]=3)CC1CCNC2.[CH:19]12[CH2:25][NH:24][CH:23]1[CH2:22][N:21]([C:26]([C:28]1[C:37]3[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=3)[CH:31]=[CH:30][C:29]=1[O:38][CH2:39][CH3:40])=[O:27])[CH2:20]2.ClC1N=C(C)C=C(C)N=1>>[CH3:12][C:11]1[CH:16]=[C:15]([CH3:14])[N:8]=[C:9]([N:24]2[CH2:25][CH:19]3[CH:23]2[CH2:22][N:21]([C:26]([C:28]2[C:37]4[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=4)[CH:31]=[CH:30][C:29]=2[O:38][CH2:39][CH3:40])=[O:27])[CH2:20]3)[N:10]=1

Participants

4

Reactant 3

HCID 205502-Chloro-4,6-dimethylpyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 67116914HCID 67116914, compound

Product 1

HCID 52919307HCID 52919307, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 24 and 2-chloro-4,6-dimethylpyrimidine. MS (ESI) mass calcd. for C24H26N4O2, 402.5; m/z found, 403.2 [M+H]+.

Sources & evidence

ORD record
ord-016cc514b430413cb6f440f3d855ca48
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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