2-Chloro-4-phenylpyrimidine → HCID 52919440, compound

HRID 1193164Notes

Reaction equation

HRID 1193164 reaction equation
C12N(C3C=NC4C(=CC=CC=4)N=3)CC1CCNC2.[CH:19]12[CH2:25][NH:24][CH:23]1[CH2:22][N:21]([C:26]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=1[N:34]1[N:38]=[CH:37][CH:36]=[N:35]1)=[O:27])[CH2:20]2.Cl[C:40]1[N:45]=[C:44]([C:46]2[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=2)[CH:43]=[CH:42][N:41]=1>>[C:46]1([C:44]2[CH:43]=[CH:42][N:41]=[C:40]([N:24]3[CH2:25][CH:19]4[CH:23]3[CH2:22][N:21]([C:26]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=3[N:34]3[N:38]=[CH:37][CH:36]=[N:35]3)=[O:27])[CH2:20]4)[N:45]=2)[CH:47]=[CH:48][CH:49]=[CH:50][CH:51]=1

Participants

4

Reactant 3

HCID 6053562-Chloro-4-phenylpyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 69932310HCID 69932310, compound

Product 1

HCID 52919440HCID 52919440, compound

Procedure

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 25 and 2-chloro-4-phenyl-pyrimidine. MS (ESI) mass calcd. for C24H21N7O, 423.48; m/z found, 424.2 [M+H]+.

Sources & evidence

ORD record
ord-514c5b3508d24afeaa89fa5df227408a
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

Loading…