2-Chloro-4-phenylpyrimidine → HCID 52919439, compound

HRID 1193166Notes

Reaction equation

HRID 1193166 reaction equation
C12[N:8]([C:9]3C=N[C:16]4[C:11](=[CH:12]C=[CH:14][CH:15]=4)[N:10]=3)CC1CCNC2.[CH:19]12[CH2:25][NH:24][CH:23]1[CH2:22][N:21]([C:26]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=1[N:34]1[N:38]=[CH:37][CH:36]=[N:35]1)=[O:27])[CH2:20]2.Cl[C:40]1N=C(C2C=CC=CC=2)C=CN=1>>[CH3:12][C:11]1[CH:16]=[C:15]([CH3:14])[N:8]=[C:9]([N:24]2[CH2:25][CH:19]3[CH:23]2[CH2:22][N:21]([C:26]([C:28]2[CH:33]=[C:32]([CH3:40])[CH:31]=[CH:30][C:29]=2[N:34]2[N:38]=[CH:37][CH:36]=[N:35]2)=[O:27])[CH2:20]3)[N:10]=1

Participants

4

Reactant 3

HCID 6053562-Chloro-4-phenylpyrimidineHCID 671166512-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 69932310HCID 69932310, compound

Product 1

HCID 52919439HCID 52919439, compound

Procedure

The title c compound was prepared in a manner analogous to Intermediate 2, Step A, using Intermediate 25 and 2-chloro-4-phenyl-pyrimidine. MS (ESI) mass calcd. for C25H23N7O, 437.51; m/z found, 438.2 [M+H]+.

Sources & evidence

ORD record
ord-54fe0d0ced3d44798f69f8139dc1f209
Source dataset
uspto-grants-2014_03
Patent number
US08680275B2

Reaction notes

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