HRID1193168

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5105623

2-(2-thienyl)benzoic acid

C11H8O2S

HCID67086689

未命名化合物

2 次

HCID68156939

未命名化合物

结构：Cc1cc(N2C[C@@H]3CCNC[C@@H]32)nc(C(F)(F)F)n1

HCID68156957

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(N2C[C@@H]3CCN(C(=O)c4ccc(C)nc4-n4ccnn4)C[C@@H]32)nc(C(F)(F)F)n1

HCID52919819

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner analogous to Example 1, substituting (1R,6S)-[8-(6-methyl-2-trifluoromethyl-pyrimidin-4-yl)-3,8-diaza-bicyclo[4.2.0]octane (Intermediate 9) for (1R,6S)8-(4,6-dimethyl-pyrimidin-2-yl)-3,8-diaza-bicyclo[4.2.0]octane and 6-methyl-2-(1H-1,2,3-triazol-1-yl)nicotinic acid (Intermediate 51) for 2-thiophen-2-yl-benzoic acid. MS (ESI) mass calcd. For C21H21F3N8O, 458.45; m/z found 459.0 [M+H]+.