huagongshe.com
HRID1193170

反应详情

EQUATION

反应方程式

HRID 1193170 的结构方程式

REACTANTS

反应物

4
结构：O=C(O)c1ccccc1-c1cccs1
HCID5105623

2-(2-thienyl)benzoic acid

C11H8O2S

结构：O=C(O)c1cc(F)ccc1-n1nccn1
HCID67086948

未命名化合物

2 次

结构：FC(F)(F)c1ccnc(N2C[C@@H]3CCNC[C@@H]32)n1
HCID67116508

未命名化合物

结构：Cc1cc(C)nc(N2C[C@@H]3CCNC[C@@H]32)n1
HCID68156939

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1cc(F)ccc1-n1nccn1)N1CC[C@H]2CN(c3nccc(C(F)(F)F)n3)[C@H]2C1
HCID52919938

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner analogous to Example 1, substituting (1R,6S)-8-(4-(trifluoromethyl)pyrimidin-2-yl)-3,8-diazabicyclo[4.2.0]octane (Intermediate 27) for (1R,6S)8-(4,6-dimethyl-pyrimidin-2-yl)-3,8-diaza-bicyclo[4.2.0]octane and 5-fluoro-2-[1,2,3]triazol-2-yl-benzoic acid (Intermediate 13) for 2-thiophen-2-yl-benzoic acid. MS (ESI) mass calcd. For C20H17F4N7O, 447.40; m/z found 448.0 [M+H]+.