HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193526Generated: November 1, 2026
Glycidol → N-{2-[(2,3-Dihydroxypropyl)amino]ethyl}-2-methylpropanamide
https://huagongshe.com/reaction/1193526
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Glycidol | HCID 11164 | — |
| Reactant | N-(2-Aminoethyl)-2-methylpropanamide | HCID 12681828 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | N-{2-[(2,3-Dihydroxypropyl)amino]ethyl}-2-methylpropanamide | HCID 14347794 | — |
Reaction Steps
To 39 g (0.3 mol) of 2-(isopropylcarbonylamino)ethylamine in 150 ml of isopropyl alcohol was added 22.2 g (0.3 mol) of glycidol. The reaction mixture was stirred at 25° C. for 24 hours and evaporated in vacuo. The residual oil was chromatographed (silica gel/ethanol) to give18.6 g (30%) of product. This compound was identified by NMR and IR spectroscopy.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04810717 |
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| Source dataset | uspto-grants-1989_03 |
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| ORD ID | ord-9761b7632295488b8f1bb72f2f47a600 |
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| Source note | uspto-grants-1989_03 |
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