Hydroxyacetate → HCID 13080193, compound

Participants

Reaction Steps

The conventional reaction of equimolar amounts of 3,5-DCI and a glycolate gives a mixture of 85-90% of an N-(3,5-dichlorophenyl)-carbamyloxyacetate (I) and 10-15% of an N,N'-bis-(3,5-dichlorophenyl)-allophanate (II), the percentages being based on 3,5-DCI employed. Both the N-(3,5-dichlorophenyl)-carbamyloxyacetate and the N,N'-bis-(3,5-dichlorophenyl)-allophanate undergo cyclization in the presence of a basic catalyst to give an N-(3,5-dichlorophenyl)-oxazolidine-2,4-dione (III), this product being obtained in a yield of about 90%, based on 3,5-DCI employed, in the case of the above mixture.

Provenance & Evidence