HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bis(4-fluorophenyl)(piperidin-4-yl)methanol → HCID 14407100, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bis(4-fluorophenyl)(piperidin-4-yl)methanol | HCID 11208889 | — |
| Reactant | HCID 12685614 | HCID 12685614 | — |
| Catalyst | Potassium Iodide | HCID 4875 | — |
| Product | HCID 14407100 | HCID 14407100 | 30% |
Reaction Steps
Following the procedure of Example 1, [α,α-bis(p-fluorophenyl)]-4-piperidinemethanol and 4-(3-chloropropoxy)benzonitrile were reacted using potassium iodide as catalyst to give the white title compound (recrystallizing from isopropyl alcohol-isopropyl ether) in 30% yield, m.p. 107°-108° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04810713 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-f46849ade08841dba6213e268d4fc01e |
| Source note | uspto-grants-1989_03 |