HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 14423288, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | HCID 14423281 | HCID 14423281 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 14423288 | HCID 14423288 | — |
Reaction Steps
React 10-(3-chlorophenyl)-6,7,8,9-tetrahydropyrido[2,3-b][1,6]naphthyridin-5(10H)-one (5 mmol) with benzylbromide (5.8 mmol) in acetone (40 ml) at 25° C. for 3 hours. Evaporate the acetone solvent, and elute the product from silca gel with chloroform to provide the product, 10-(3-chlorophenyl)-6,7,8,9-tetrahydro-7-N-benzyl-pyrido[2,3-b][1,6]naphthyridin-5(10H)-one, m.p. 157°-161° C. after crystallization from CH3CN.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04810708 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-d359d2af49f54537b94dad71043d079a |
| Source note | uspto-grants-1989_03 |