Allyl bromide → HCID 21270708, compound

HRID 1193897Notes

Reaction equation

HRID 1193897 reaction equation
[Cl:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([N:9]2[C:14](=[O:15])[CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[N:11]=[C:10]2[O:20][CH3:21])=[C:4]([F:22])[CH:3]=1.[CH2:23](Br)[CH:24]=[CH2:25].C(=O)([O-])[O-].[Na+].[Na+]>CC(C)=O>[CH2:25]([O:8][C:7]1[C:2]([Cl:1])=[CH:3][C:4]([F:22])=[C:5]([N:9]2[C:14](=[O:15])[CH:13]=[C:12]([C:16]([F:18])([F:17])[F:19])[N:11]=[C:10]2[O:20][CH3:21])[CH:6]=1)[CH:24]=[CH2:23]

Participants

5

Reactant 3

HCID 7841Allyl bromideHCID 10340Sodium CarbonateHCID 21270742HCID 21270742, compound

Product 1

HCID 21270708HCID 21270708, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

using 1-(4-chloro-2-fluoro-5-hydroxyphenyl)-2-methoxy-4-trifluoromethyl-6(1H)-pyrimidinone and allyl bromide with sodium carbonate in acetone there is obtained 1-(5-allyloxy-4-chloro-2-fluorophenyl)-2-methoxy-4-trifluoromethyl-6(1H)-pyrimidinone, m.p. 103°-104° C.;

Sources & evidence

ORD record
ord-cefc1571b3b94fa889d6902b66270867
Source dataset
uspto-grants-1989_03
Patent number
US04812164

Reaction notes

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