Dimethyl Sulfate → HCID 21270722, compound

HRID 1193898Notes

Reaction equation

HRID 1193898 reaction equation
[Cl:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([N:9]2[C:14](=[O:15])[CH:13]=[C:12]([C:16]([F:22])([F:21])[C:17]([F:20])([F:19])[F:18])[N:11]=[C:10]2[O:23][CH3:24])=[C:4]([F:25])[CH:3]=1.S(OC)(O[CH3:30])(=O)=O.C(=O)([O-])[O-].[Na+].[Na+]>CC(C)=O>[Cl:1][C:2]1[C:7]([O:8][CH3:30])=[CH:6][C:5]([N:9]2[C:14](=[O:15])[CH:13]=[C:12]([C:16]([F:21])([F:22])[C:17]([F:20])([F:18])[F:19])[N:11]=[C:10]2[O:23][CH3:24])=[C:4]([F:25])[CH:3]=1

Participants

5

Reactant 3

HCID 6497Dimethyl SulfateHCID 10340Sodium CarbonateHCID 21270776HCID 21270776, compound

Product 1

HCID 21270722HCID 21270722, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

using 1-(4-chloro-2-fluoro-5-hydroxyphenyl)-2-methoxy-4-pentafluoroethyl-6(1H)-pyrimidinone and dimethyl sulphate with sodium carbonate in acetone there is obtained 1-(4-chloro-2-fluoro-5-methoxyphenyl)-2-methoxy-4-pentafluoroethyl-6(1H)-pyrimidinone. m.p. 123°-125° C.;

Sources & evidence

ORD record
ord-718599ba522340c486c3a76d64ca9288
Source dataset
uspto-grants-1989_03
Patent number
US04812164

Reaction notes

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