Propargyl bromide → HCID 53689805, compound

Participants

Reaction Steps

using 1-(4-chloro-2-fluoro-5-hydroxyphenyl)-2-methoxy-4-pentafluoroethyl-6(1H)-pyrimidinone and propargyl bromide with sodium carbonate in acetone there is obtained 1-[4-chloro-2-fluoro-5-(2-propynyloxy) -phenyl]-2-methoxy-4-pentafluoroethyl-6(1H)-pyrimidinone, 1H-NMR (CDCl3, 400 MHz): 7.35 ppm (d,1H), 6.98 ppm (d,1H), 6.67 ppm (s,1H), 4.77 ppm (m,2H), 3.99 ppm (s,3H), 2.58 ppm (t,1H);

Provenance & Evidence