Potassium Nitrate → HCID 178526421, compound

HRID 1193971Notes

Reaction equation

HRID 1193971 reaction equation
[N+:1]([O-:4])([O-])=[O:2].[K+].[Cl:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[N:13]=[C:12]([OH:17])[C:11]([OH:18])=[N:10]2>S(=O)(=O)(O)O>[Cl:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][C:16]=1[N+:1]([O-:4])=[O:2])[N:13]=[C:12]([OH:17])[C:11]([OH:18])=[N:10]2

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 178517169HCID 178517169, compound

Product 1

HCID 178526421HCID 178526421, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Finely powdered potassium nitrate (1.01 g, 10 mmol) was added during 5 min. to a stirred solution of 6-chloro-2,3-dihydroxyquinoxaline (1.97 g, 10 mmol) in 50 ml of conc. sulfuric acid at 0° C. (icebath). After 1 h the icebath was removed and stirring was continued for 21/2 h at room temperature. The mixture was poured into 200 ml of ice/water and the precipitate was isolated, washed with water, ethanol, and ether. The product was dissolved in 70 ml of hot 2N sodium hydroxide, filtered while hot, and reprecipitated with conc. hypochloric acid to give 2.12 g (88%) of pure title compound; m.p. >300° C.;

Workup

  1. customAfter 1 h the icebath was removed
  2. custom2 h
  3. customat room temperature
  4. additionThe mixture was poured into 200 ml of ice/water
  5. customthe precipitate was isolated
  6. washwashed with water, ethanol, and ether
  7. dissolutionThe product was dissolved in 70 ml of hot 2N sodium hydroxide
  8. filtrationfiltered while hot, and
  9. customreprecipitated with conc. hypochloric acid

Sources & evidence

ORD record
ord-3c08291f2cf14d24b3000358fc38c341
Source dataset
uspto-grants-1989_03
Patent number
US04812458

Reaction notes

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