Ammonia → 1H-Isoindole-1,3(2H)-dione, hexahydro-

HRID 1193989Notes

Reaction equation

HRID 1193989 reaction equation
[CH:1]12[C:10](=[O:11])O[C:7](=[O:8])[CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6]2.[NH3:12]>>[CH:1]12[C:10](=[O:11])[NH:12][C:7](=[O:8])[CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6]2

Participants

3

Reactant 2

HCID 222AmmoniaHCID 85689Hexahydrophthalic anhydride

Product 1

HCID 735591H-Isoindole-1,3(2H)-dione, hexahydro-

Procedure

A mixture of cyclohexane-1,2-dicarboxylic anhydride (3 g; 19.5 mmol) and 29% aqueous ammonia (3.4 g) was heated to and kept at an inner temperature of 180 to 190° C. for 2 hours to give the objective compound quantitatively. M.P., 132°-136° C.

Workup

  1. temperaturewas heated to and
  2. customto give the objective compound quantitatively
  3. customM.P., 132°-136° C.

Sources & evidence

ORD record
ord-d641175244c94ca3955d21737bd34efe
Source dataset
uspto-grants-1989_03
Patent number
US04812461

Reaction notes

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