HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,6-Trimethylphenol → 3-Tert-butyl-2-(2,4,6-trimethylphenoxy)-1,3,2-oxazaphospholidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,6-Trimethylphenol | HCID 10698 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-tert-Butyl-2-chloro-1,3,2-oxazaphospholidine | HCID 14228109 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Tert-butyl-2-(2,4,6-trimethylphenoxy)-1,3,2-oxazaphospholidine | HCID 14228110 | 75.6% |
Reaction Steps
The procedure of Example 1 is repeated using 4.4 g (0.11 mol) of sodium hydride with 45 ml of THF, 13.62 g (0.10 mol) of 2,4,6-trimethylphenol in 150 ml of THF and 18.16 g (0.10 mol) of 3-tert-butyl-2-chloro-1,3,2-oxazaphospholidine in 150 ml of THF to give a (75.6%) of colorless liquid: bp. 99°-103° C. (0.01 mm Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04812501 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-b5a7ecbee14849c7a1d045da447b7e48 |
| Source note | uspto-grants-1989_03 |