Methyl vinyl ketone → HCID 21269563, compound

HRID 1194342Notes

Reaction equation

HRID 1194342 reaction equation
[CH2:1]([C:8]1[CH:17]=[CH:16][C:11]2[NH:12][C:13](=[S:15])[NH:14][C:10]=2[CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:18][C:19]([CH:21]=[CH2:22])=[O:20]>>[O:20]=[C:19]([CH3:18])[CH2:21][CH2:22][N:12]1[C:11]2[CH:16]=[CH:17][C:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)=[CH:9][C:10]=2[N:14]([CH2:22][CH2:21][C:19](=[O:20])[CH3:18])[C:13]1=[S:15]

Participants

3

Reactant 2

HCID 6570Methyl vinyl ketoneHCID 21269540HCID 21269540, compound

Product 1

HCID 21269563HCID 21269563, compound

Procedure

14.4 g (60 mmoles) of 5-benzyl-benzimidazoline-2-thione amd 45 ml of methylvinylketone are boiled for 4 hours in the presence of 2 drops of 40%, methynolic Triton B solution. Then the reaction mixture is evaporated off. During storage the distillation residue crystallizes. This is recrystallized from 200 ml of ethanol and thus 19.86 g (87%) of title product melting at a temperature of 98°-100° C. are obtained.

Workup

  1. customThen the reaction mixture is evaporated off
  2. customDuring storage the distillation residue crystallizes
  3. customThis is recrystallized from 200 ml of ethanol and thus 19.86 g (87%) of title product
  4. custommelting at a temperature of 98°-100° C.
  5. customare obtained

Sources & evidence

ORD record
ord-a3ff598f680f4748bbac063bde8880af
Source dataset
uspto-grants-1989_03
Patent number
US04814329

Reaction notes

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