HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 3-(1H-Imidazol-1-yl)-1-(1H-indol-3-yl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 3-(3-Dimethylaminopropionyl)indole | HCID 32750 | — |
| Product | 3-(1H-Imidazol-1-yl)-1-(1H-indol-3-yl)propan-1-one | HCID 21270059 | — |
Reaction Steps
3-(Dimethylamino)-1-(1H-indol-3-yl)-1-propanone was converted to the methiodide (12.75 g) which was then reacted with imidazole (12.75 g) to give the title compound (4.67 g), m.p. 193°-197°; λmax (EtOH) 242.5 nm (ε11,130), λinf 257.5 nm (ε9,120), λmax 299 nm (ε12,420), identical with the material obtained in Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04814344 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-ab5bf2e4e4444631aece17efbf5af0e0 |
| Source note | uspto-grants-1989_03 |