1-(triphenylmethyl)-1H-imidazole-4-carbaldehyde → alpha-(4H-1,3-Benzodioxin-6-yl)-1-triphenylmethyl-1H-imidazole-4-methanol

Participants

Reaction Steps

This compound is prepared like the preceding compound but starting from 6-bromo-4H-1,3-benzodioxin and 1-triphenylmethyl-1H-imidazole-4-carboxaldehyde. After decomposing the reaction mixture, the reaction product is extracted with dichloromethane and recrystallized from isopropyl alcohol. By chromatography of the residue obtained after evaporation of the mother liquors, there is obtained a second crop of product. Yield: 53% of theory; M.P.: 165°-167° C.

Provenance & Evidence