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HRID1194372

反应详情

EQUATION

反应方程式

HRID 1194372 的结构方程式

REACTANTS

反应物

2
结构：Cn1cnc(C=O)c1
HCID573419

1-Methyl-1H-imidazole-4-carbaldehyde

C5H6N2O

结构：CC1(C)OCc2cc(Cl)cc(Br)c2O1
HCID14520336

8-Bromo-6-chloro-2,2-dimethyl-4H-1,3-benzodioxin

C10H10BrClO2

PRODUCTS

生成物

1
结构：Cn1cnc(C(O)c2cc(Cl)cc3c2OC(C)(C)OC3)c1
HCID14520341

未命名化合物

收率 63.5%

PROCEDURE

实验过程

Starting from 8-bromo-6-chloro-2,2-dimethyl-4H-1,3-benzodioxin and 1-methyl-1H-imidazole-4-carboxaldehyde. The addition of the organomagnesium compound is carried out at 0° C. Yield: 63.5% of theory; M.P.: 131°-136° C. (recrystallized from ethyl acetate).

WORKUP

后处理

  1. customis carried out at 0° C
  2. customM.P.: 131°-136° C. (recrystallized from ethyl acetate)