HRID1194376

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID618233

1-Tritylimidazole-4-carboxaldehyde

C23H18N2O

HCID14520331

未命名化合物

PRODUCTS

生成物

结构：COCc1ccc(OC)c(C(O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1OC

HCID21269997

未命名化合物

收率 48%

PROCEDURE

实验过程

Starting from 1-bromo-2,6-dimethoxy-3-methoxymethylbenzene and 1-triphenylmethyl-1H-imidazole-4-carboxaldehyde. The reaction product is purified by chromatography on silica and is present in the form of a glassy lac. Yield: 48% of theory.

WORKUP

后处理

customThe reaction product is purified by chromatography on silica

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6ffc884b3d924c74943d1107e4e7f1cd
来源数据集: uspto-grants-1989_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04814343
来源说明: uspto-grants-1989_03

反应 SMILES

Br[C:2]1[C:7]([O:8][CH3:9])=[CH:6][CH:5]=[C:4]([CH2:10][O:11][CH3:12])[C:3]=1[O:13][CH3:14].[C:15]1([C:21]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[N:22]2[CH:26]=[C:25]([CH:27]=[O:28])[N:24]=[CH:23]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH3:14][O:13][C:3]1[C:4]([CH2:10][O:11][CH3:12])=[CH:5][CH:6]=[C:7]([O:8][CH3:9])[C:2]=1[CH:27]([C:25]1[N:24]=[CH:23][N:22]([C:21]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)[C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH:26]=1)[OH:28]