HCID 14520347, compound → HCID 178431336, compound

HRID 1194384Notes

Reaction equation

HRID 1194384 reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]([C:14]([CH3:40])([C:16]2[N:17]=[CH:18][N:19](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH:20]=2)[OH:15])[C:5]2[O:6][C:7]([CH3:11])([CH3:10])[O:8][CH2:9][C:4]=2[CH:3]=1>C(OCC)C>[ClH:1].[CH3:10][C:7]1([CH3:11])[O:6][C:5]2[C:12]([C:14]([CH3:40])([C:16]3[N:17]=[CH:18][NH:19][CH:20]=3)[OH:15])=[CH:13][CH:2]=[CH:3][C:4]=2[CH2:9][O:8]1

Participants

3

Reactant 1

HCID 14520347HCID 14520347, compound

Product 1

HCID 178431336HCID 178431336, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The process is exactly the same as in 2. above but a temperature of 20° C. is used, starting from alpha-(6-chloro-2,2-dimethyl-4H-1,3-benzodioxin-8-yl)-alpha-methyl-1-triphenylmethyl-1H-imidazole-4-methanol (prepared in Example 2.B.2.). The yield is practically quantitative; M.P.: 85°-100° C. (decomposition). An analytical sample is prepared by stirring in diethyl ether; M.P.: 72°-90° C. (decomposition).

Workup

  1. customa temperature of 20° C.
  2. customAn analytical sample is prepared

Sources & evidence

ORD record
ord-45bc7e39ee8b4a50acff15c91a2b7414
Source dataset
uspto-grants-1989_03
Patent number
US04814343

Reaction notes

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