HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxylic Acid → Trans 4-(2,5-dimethyl-3-furyl)-4-oxo-2-butenoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxylic Acid | HCID 760 | — |
| Reactant | 3-Acetyl-2,5-dimethylfuran | HCID 61527 | — |
| Solvent | Water | HCID 962 | — |
| Product | Trans 4-(2,5-dimethyl-3-furyl)-4-oxo-2-butenoic Acid | HCID 13565867 | 14.2% |
Reaction Steps
As in Example 1, one starts out with 9 g of 3-acetyl 2.5-dimethylfuran (J. Am. Chem. Soc., 70 739 (1948)), 6 g glyoxylic acid and 6 cm3 water. Following chromatography on silica (eluent: petroleum ether-ethyl acetate (2-8), recrystallization in ethyl acetate, 1.8 g of the expected product is obtained. MP=144°-147° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04814348 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-4330fc5aab404c76bd4b258c5d74099b |
| Source note | uspto-grants-1989_03 |