HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1194402Generated: October 30, 2026
Potassium Hydroxide → 1-(3-Phenoxy-4-fluorophenyl)-4-(4-methoxyphenyl)-4-methyl-1-penten-3-one
https://huagongshe.com/reaction/1194402
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 4-Fluoro-3-phenoxybenzaldehyde | HCID 110068 | — |
| Reactant | 3-(4-Methoxyphenyl)-3-methylbutan-2-one | HCID 11127109 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(3-Phenoxy-4-fluorophenyl)-4-(4-methoxyphenyl)-4-methyl-1-penten-3-one | HCID 54086169 | 32.6% |
Reaction Steps
A mixture of 7.6 g of 2-(4-methoxyphenyl)-2-methyl-3-butanone, 8.5 g of 3-phenoxy-4-fluorobenzaldehyde, 30 ml of methanol and 2 g of KOH was stirred at 60° C. for two hours. In the same manner as described in (a) of (1) of Synthesis Example 1, the reaction mixture was treated to give 5 g of 1-(3-phenoxy-4-fluorophenyl)-4-(4-methoxyphenyl)-4-methyl-1-penten-3-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04814340 |
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| Source dataset | uspto-grants-1989_03 |
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| ORD ID | ord-1973684e918c4b39855eddda09da9102 |
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| Source note | uspto-grants-1989_03 |
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